Peritoneal cavity and extraperitoneal pelvis. Less commonly, soft-tissue sarcomas originate in the The retroperitoneum and trunk wall are the most common locations for soft-tissue Sarcomas arising in solid visceral organs, such as the liver, spleen, and uterus, are An emphasis is placed on establishing an appropriateĭifferential diagnosis on the basis of the anatomic location and radiologic features. In this article, theĬlinical-pathologic and radiologic features of the most common abdominal and pelvic Initial diagnosis is essential for these patients. Soft-tissue sarcomas are rare and can be difficult to treat and manage, an accurate However, knowledge of the imaging and pathologicįeatures of soft-tissue sarcomas is important in the differential diagnosis. In the abdomen and pelvis may occur in all anatomic compartments, the retroperitoneum, The differentialĭiagnosis will depend primarily on the anatomic location. Pelvic mass in a patient who is imaged for abdominal fullness or pain. The typical scenario is the discovery of a large abdominal or The presenting clinical manifestations and often the imaging findings of soft-tissue GIST gastrointestinal stromal tumor is also an important tumor for radiologists to recognize andĭifferentiate from other intra-abdominal and gastrointestinal malignancies because of Most important changes in the updated WHO World Health Organization classification ( Table 1) GIST gastrointestinal stromal tumor is included in this discussion because of its inclusion in the 2013 WHO World Health Organization classification of soft-tissue sarcomas this inclusion was one of the Stromal tumor (GIST gastrointestinal stromal tumor) is the most common gastrointestinal and intraperitoneal sarcoma. Retroperitoneum is their most common location. Leiomyosarcoma are the most common intra-abdominal soft-tissue sarcomas, and the (specifically, well-differentiated and dedifferentiated liposarcomas) and Retroperitoneum, and 9% in the head and neck ( 3). Originate in an extremity (most commonly, the thigh), 19% in the trunk wall, 15% in the Approximately 60% of soft-tissue sarcomas States in 2016 is 12 310 cases, and the number of estimated deaths is 4990 ( 2). The estimated number of new soft-tissue sarcomas in the United Soft-tissue sarcomasĪffect all ages and may arise at any location in the body. Health Organization (WHO World Health Organization) divides sarcomas into two broad categories: sarcomas of soft tissueĪnd sarcomas of bone ( 1). Sarcomas are a large, diverse group of malignant tumors of mesenchymal origin. Part 2 will focus on the remainder of the soft-tissue sarcomas occurring Sarcomas (liposarcoma, leiomyosarcoma, and GIST) are reviewed, with a discussion onĪnatomic locations, classification, clinical considerations, and differentialĭiagnosis. In part 1 of this article, the most common soft-tissue Soft-tissue sarcomas, the anatomic locations where they occur, and theirĬross-sectional imaging features helps the radiologist establish the diagnosis orĭifferential diagnosis so that patients with soft-tissue sarcomas can receive optimal Knowledge of the classification and pathologic features of Any soft-tissue sarcoma can arise in theĪbdominal wall. Liposarcomas), leiomyosarcoma, and gastrointestinal stromal tumor (GIST) are the mostĬommon intra-abdominal primary sarcomas. Liposarcoma (well-differentiated and dedifferentiated Overlap with more common pathologic conditions, making diagnosis difficult or, in The imaging features ofĪbdominal and pelvic sarcomas and abdominal wall sarcomas can be nonspecific and Soft-tissue sarcomas arising from the abdominal wall come to clinical attentionĮarlier in the course of disease because they cause a palpable mass, abdominal wallĭeformity, or pain that is more clinically apparent. Large masses at the time of diagnosis because they are usually clinically silent orĬause vague or mild symptoms until they invade or compress vital organs.
In theĪdult population, soft-tissue sarcomas arising in the abdomen and pelvis are often These sarcomas are mostĬommon in the extremities, trunk wall, retroperitoneum, and head and neck. Soft-tissue sarcomas are a diverse group of rare mesenchymal malignancies that canĪrise at any location in the body and affect all age groups.
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